Smith, Rhett C. Department of Chemistry and Biochemistry, Clemson University, Clemson, South Carolina.
- Links to Primary Literature
The study of metal ion function in the brain and nervous system at the molecular level. Stephen J. Lippard coined the term metalloneurochemistry in 2003 to describe this area of chemistry. The field has expanded in the past few years to include inorganic species other than metal ions. Metalloneurochemistry is thus an acutely interdisciplinary field requiring researchers in the area to have knowledge of biology, biochemistry, and inorganic chemistry. Although this challenging field was formulated just over a decade ago, its advent has spurred an incredible volume of research that has contributed significantly to understanding the complex and vital role of metal ions in both healthy and disease states. Some neurodegenerative diseases in which metal ions play a definite role include amyotrophic lateral sclerosis (ALS), Alzheimer's disease, transmittable spongiform encephalitis (prion diseases), and Parkinson's disease. These few examples of currently incurable conditions highlight the importance of understanding the molecular basis for the deleterious effects of such disease and injury states so that rationally designed preventative and curative medicines can be developed. See also: Alzheimer's disease; Metal ions in neurodegenerative diseases of protein misfolding; Parkinson's disease; Prion disease
The content above is only an excerpt.
for your institution. Subscribe
To learn more about subscribing to AccessScience, or to request a no-risk trial of this award-winning scientific reference for your institution, fill in your information and a member of our Sales Team will contact you as soon as possible.
to your librarian. Recommend
Let your librarian know about the award-winning gateway to the most trustworthy and accurate scientific information.
AccessScience provides the most accurate and trustworthy scientific information available.
Recognized as an award-winning gateway to scientific knowledge, AccessScience is an amazing online resource that contains high-quality reference material written specifically for students. Its dedicated editorial team is led by Sagan Award winner John Rennie. Contributors include more than 9000 highly qualified scientists and 42 Nobel Prize winners.
MORE THAN 8500 articles and Research Reviews covering all major scientific disciplines and encompassing the McGraw-Hill Encyclopedia of Science & Technology and McGraw-Hill Yearbook of Science & Technology
115,000-PLUS definitions from the McGraw-Hill Dictionary of Scientific and Technical Terms
3000 biographies of notable scientific figures
MORE THAN 17,000 downloadable images and animations illustrating key topics
ENGAGING VIDEOS highlighting the life and work of award-winning scientists
SUGGESTIONS FOR FURTHER STUDY and additional readings to guide students to deeper understanding and research
LINKS TO CITABLE LITERATURE help students expand their knowledge using primary sources of information